अमायलॉयडोसिस: अमायलॉयडोसिसमध्ये असामान्य प्रथिने हृदय, मूत्रपिंड व नसांमध्ये साचतात. पायावर सूज, लघवीत फेस, धाप, हातापायांना मुंग्या येणे ही लक्षणे आहेत. लवकर निदान अत्यंत महत्त्वाचे आहे.
एमिलॉयडोसिस: एमिलॉयडोसिस में असामान्य प्रोटीन दिल, किडनी और नसों में जमा हो जाता है। पैरों में सूजन, पेशाब में झाग, सांस फूलना, हाथ-पैर में झनझनाहट इसके लक्षण हैं।
Amyloidosis is a condition in which an abnormal protein (amyloid) is deposited in organs such as the heart, kidneys, nerves and liver. AL amyloidosis comes from abnormal plasma cells in the bone marrow and is treated by a haematologist.
Symptoms
- Swelling of feet, frothy urine (protein loss)
- Breathlessness, low blood pressure, irregular heartbeat
- Numbness or tingling of hands and feet
- Large tongue, easy bruising around the eyes
Diagnosis
Urine protein, serum free light chains and electrophoresis, heart tests (ECHO, NT-proBNP, troponin), and a tissue biopsy (fat pad, bone marrow or organ) with special staining and typing.
Treatment
Treatment is similar to myeloma – combinations including bortezomib and daratumumab – with careful support of heart and kidney function. Early treatment can stop further organ damage.