रोगप्रतिकारशक्तीचे विकार: मुलांना किंवा मोठ्यांना वारंवार गंभीर जंतुसंसर्ग (न्यूमोनिया, कानाचे, त्वचेचे संसर्ग) होत असतील तर रोगप्रतिकारशक्तीतील दोष असू शकतो. योग्य तपासणी व उपचार उपलब्ध आहेत.
रोग प्रतिरोधक क्षमता की कमी के विकार: बच्चों या बड़ों को बार-बार गंभीर संक्रमण (निमोनिया, कान, त्वचा) हो तो रोग प्रतिरोधक क्षमता में कमी हो सकती है।
Immune deficiency disorders weaken the body's defence against infection. They may be inherited (primary) – usually showing in childhood – or acquired (secondary), due to cancer treatment, steroids, malnutrition, HIV or blood cancers such as CLL and myeloma.
Warning signs
- Two or more pneumonias in a year, or repeated ear and sinus infections
- Infections needing intravenous antibiotics, or unusual infections
- Poor growth in a child, chronic diarrhoea, persistent oral thrush
- Family history of immune deficiency or early childhood deaths
Evaluation
Blood counts, immunoglobulin levels, lymphocyte subsets (flow cytometry), vaccine response and genetic testing.
Treatment
Prevention of infections, appropriate vaccines, antibiotic prophylaxis, immunoglobulin replacement (IVIG) in day care, and transplant consultation for selected severe inherited disorders.