टार्गेटेड थेरपी: टार्गेटेड थेरपी कर्करोगाच्या पेशींमधील विशिष्ट बदलांवर (म्युटेशन) काम करते. यासाठी बायोप्सीवर विशेष चाचण्या कराव्या लागतात. अनेक औषधे गोळ्यांच्या स्वरूपात घरी घेता येतात.
टार्गेटेड थेरेपी: टार्गेटेड थेरेपी कैंसर कोशिकाओं के विशेष बदलावों (म्यूटेशन) पर काम करती है। इसके लिए बायोप्सी पर विशेष जांच होती है। कई दवाएं गोलियों के रूप में घर पर ली जा सकती हैं।
Targeted therapies act on specific changes (mutations or proteins) that help a cancer grow. They work only when the target is present, so testing the tumour comes first.
Examples
- Lung cancer: EGFR, ALK, ROS1, KRAS G12C and other inhibitors – often once-daily tablets
- Breast cancer: HER2-targeted antibodies (trastuzumab, pertuzumab), CDK4/6 inhibitors with hormone therapy
- Blood cancers: imatinib and other tablets for CML; BTK inhibitors for CLL; rituximab for lymphoma
- Ovarian and prostate cancer: PARP inhibitors for BRCA-mutated cancers
- Colorectal, kidney, liver, thyroid and other cancers
Tests that guide targeted therapy
Immunohistochemistry, FISH, PCR and next-generation sequencing (NGS) on the biopsy or a blood sample (liquid biopsy). We help you choose the right test and the right laboratory.
Cost and access
Many targeted drugs now have affordable generic or biosimilar versions in India, and patient-assistance programmes are available for several drugs. We are registered for compassionate-access programmes and will guide you.